Pain Sensitization and Descending Pain Inhibition in Fibromyalgia
Impaired endogenous pain inhibition contributes to pain sensitization in FM and may partly explain SREP sensitization. This reduced pain inhibition could also underlie the clinical symptoms commonly seen in FM. Future research may clarify the altered balance between ascending and descending pain processes in FM.
Authors
- Stefan Duschek (ORCID: https://orcid.org/0000-0002-9082-0154)
- Pablo de la Coba (ORCID: https://orcid.org/0000-0001-6469-3553)
- A Hernández (ORCID: https://orcid.org/0000-0003-2559-6181)
- Stephen Bruehl (ORCID: https://orcid.org/0000-0003-2264-4758)
- Gustavo A. Reyes del Paso (ORCID: https://orcid.org/0000-0002-2188-8673)
Institutions
- Universidad de Jaén (ES)
- Universidad de Extremadura (ES)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Clinical Journal of Pain
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1097/ajp.0000000000001327
- Citations
- 2
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 2.94