Mid‐Regional Proadrenomedullin in Cerebrospinal Fluid Is a Reliable Diagnostic and Prognostic Marker for Acute Meningoencephalitis and Neurological Disorders
We demonstrated significant upregulation of Adrenomedullin in CSF during infections compared to other neurological diseases and proposed preliminary thresholds of CSF MR-proADM to be used in the diagnostic workup of acute CNS infections, to help with differential diagnosis and possibly guide targeted therapeutic interventions.
Authors
- Silvia Leonardi
- Novella Carannante (ORCID: https://orcid.org/0000-0002-7826-1820)
- Marco Comar
- Mariarosaria Valente (ORCID: https://orcid.org/0000-0001-6077-1315)
- Martina Fabris (ORCID: https://orcid.org/0000-0002-9745-2841)
- Francesco Curcio (ORCID: https://orcid.org/0000-0002-9070-4807)
- Daniela Visentini
- Francesco Janes (ORCID: https://orcid.org/0000-0003-1534-1409)
- Matteo Furlani
- Carlo Tascini (ORCID: https://orcid.org/0000-0001-9625-6024)
- Francesco Sbrana (ORCID: https://orcid.org/0000-0003-4607-0373)
- Andrea Ripoli
- Paola Dalla Siega
- Agnese Zanus Fortes
Institutions
- University of Udine (IT)
- Ospedale Monaldi (IT)
- Ospedale D. Cotugno (IT)
- Fondazione Toscana Gabriele Monasterio (IT)
Publication Details
- Journal
- Journal of Clinical Laboratory Analysis
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1002/jcla.70110
- Citations
- 1
- Primary Topic
- Neuropeptides and Animal Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.91