Accelerated Optimized Protocol of Intermittent Theta-Burst Stimulation for Negative Symptoms in Schizophrenia (ACTh-NS): A Randomized, Double-Blind, Sham-Controlled Study Design
The accelerated iTBS protocol has demonstrated promising effects on NSs. However, it is still necessary to establish an effective and feasible high-dosage protocol. This study will contribute to optimizing therapeutic protocols for schizophrenia, with a particular focus on clinical applicability. Additionally, it will provide an opportunity to deepen the understanding of the physiological effects of neuromodulation, contributing to the understanding of its underlying mechanisms.
Authors
- L Jorge
- Carolina Ziebold (ORCID: https://orcid.org/0000-0002-7965-6680)
- July Silveira Gomes (ORCID: https://orcid.org/0000-0003-3048-2867)
- Ivan Taiar (ORCID: https://orcid.org/0000-0003-0487-7339)
- André Fernandes (ORCID: https://orcid.org/0000-0002-9048-703X)
- Pedro G. Lorencetti (ORCID: https://orcid.org/0000-0002-3374-8838)
- André R. Brunoni (ORCID: https://orcid.org/0000-0002-6310-3571)
- Ary Gadelha (ORCID: https://orcid.org/0000-0002-0993-8017)
- Renan M Biokino
Institutions
- Universidade de São Paulo (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3390/brainsci15091021
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00