TAGAP restrains myeloid and T cell activation in inflammatory bowel disease
These findings demonstrated the role of TAGAP in immune responses and homeostasis. The E147K variant underscores TAGAP's protective function in IBD, and further investigation is warranted to translate these insights into therapeutic strategies for autoimmune diseases.
Authors
- RuiCi Lin (ORCID: https://orcid.org/0000-0002-8748-2676)
- Zhifei Shao
Institutions
- Inflammation Research Foundation (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1641365
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amgen