Ultrasound-Guided Prolotherapy for Sciatica Secondary to Sacrospinous Ligament Calcification: A Potential and Previously Overlooked Etiological Factor in Deep Gluteal Syndrome—A Case Report and Literature Review

This case highlights isolated sacrospinous ligament calcification as a potential and previously overlooked pathological entity responsible for deep gluteal syndrome. To our knowledge, this is the first report to implicate ligamentous calcification as a primary etiological factor in DGS. Musculoskeletal ultrasound proved indispensable for both diagnosis and treatment guidance. Furthermore, ultrasound-guided prolotherapy emerged as a successful and minimally invasive therapeutic option in this case, potentially by stabilizing the ligament and reducing neurogenic inflammation. This case expands the differential diagnosis of sciatica, introduces a new target for intervention in refractory cases, and underscores the need for future studies in larger patient cohorts to validate these findings.

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Publication Details

Journal
Life
Published
2025-09-22
DOI
https://doi.org/10.3390/life15091486
Citations
3
Primary Topic
Shoulder Injury and Treatment
Type
article
Field-Weighted Citation Impact
6.02
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article

Ultrasound-Guided Prolotherapy for Sciatica Secondary to Sacrospinous Ligament Calcification: A Potential and Previously Overlooked Etiological Factor in Deep Gluteal Syndrome—A Case Report and Literature Review

Daniel Chiung‐Jui Su, Yonghyun Yoon, King Hei Stanley Lam, Kenneth Dean Reeves et al.
3 citations
Life
Shoulder Injury and Treatment
6.02
article

Ultrasound-Guided Prolotherapy for Sciatica Secondary to Sacrospinous Ligament Calcification: A Potential and Previously Overlooked Etiological Factor in Deep Gluteal Syndrome—A Case Report and Literature Review

Daniel Chiung‐Jui Su, Yonghyun Yoon, King Hei Stanley Lam, Kenneth Dean Reeves, Jaeyoung Lee, Jong-Hyeok Lee, Jae‐Hyun Shim, RM Park, Stephen Cavallino
article en
3 citations

Abstract

This case highlights isolated sacrospinous ligament calcification as a potential and previously overlooked pathological entity responsible for deep gluteal syndrome. To our knowledge, this is the first report to implicate ligamentous calcification as a primary etiological factor in DGS. Musculoskeletal ultrasound proved indispensable for both diagnosis and treatment guidance. Furthermore, ultrasound-guided prolotherapy emerged as a successful and minimally invasive therapeutic option in this case, potentially by stabilizing the ligament and reducing neurogenic inflammation. This case expands the differential diagnosis of sciatica, introduces a new target for intervention in refractory cases, and underscores the need for future studies in larger patient cohorts to validate these findings.

LifeVol. 15(9)
U.S. National Science Foundation (US), Hallym University (KR), Chinese University of Hong Kong (HK), Inha University (KR), Yonsei University (KR), European Polytechnical University (BG), International Bar Association (GB), Kowloon Hospital (CN), Kyung Hee University (KR), Tissue Regeneration Systems (United States) (US), Hallym University Kangnam Sacred Heart Hospital (KR), Rehabilitation Institute of Kansas City (US), Chi Mei Medical Center (TW), National Rehabilitation Center (KR), Metric Systems Corporation (United States) (US), Incheon Medical Center (KR), Neurology, Inc (US), University of Hong Kong (HK)
Openalex Percentile: Top 3%
Shoulder Injury and Treatment
6.02
DOIOpen Access PDFOpenAlex
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