Gut Microbial Metabolite Butyrate Regulates Treg/Th17 Cell Balance to Alleviate Diabetic Periodontitis
Gut microbiota dysbiosis contributes to diabetic periodontitis progression through disruption of the Treg/Th17 balance, whereas butyrate, as an immunomodulatory SCFA, may alleviate periodontal tissue destruction by restoring this balance.
Authors
- Shuguo Zheng (ORCID: https://orcid.org/0000-0001-6717-5196)
- Yifan Xu (ORCID: https://orcid.org/0000-0002-8999-2565)
- C Yuan (ORCID: https://orcid.org/0000-0001-7244-0994)
- Jing Diao (ORCID: https://orcid.org/0000-0002-2478-7659)
- Yanling Zhang (ORCID: https://orcid.org/0000-0001-6344-8804)
- Wenying Yang
Institutions
- Stomatology Hospital (CN)
Publication Details
- Journal
- Journal Of Clinical Periodontology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1111/jcpe.70041
- Citations
- 6
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 8.79