Fit but not immune from the risk: the hidden burden of dyslipidemia in elite athletes

Elite athletes are widely perceived to possess exceptional cardiovascular health due to their high levels of physical activity. However, emerging evidence suggests that among the established cardiovascular risk factors, dyslipidemia remains prevalent and frequently under-recognized in this population. Despite their athletic status, elite competitors, including Olympic and Paralympic athletes, may exhibit lipid abnormalities influenced by a complex interplay of factors such as sport type, training intensity, gender, ethnicity and disability status. This review aims to provide a comprehensive overview of dyslipidemia in elite athletes, exploring its prevalence, contributing physiological and lifestyle factors, clinical consequences and current approaches to assessment and management. Special attention is given to population-specific considerations, including gender, sport type and ethnicity. The limitations of general population cardiovascular risk scores in this context are discussed, with a focus on the need for athlete-specific tools such as the proposed "Lipid Athlete Score." Management strategies, ranging from lifestyle modification to the cautious use of pharmacologic agents and emerging nutraceutical interventions, are critically evaluated. Finally, the review highlights gaps in current research and outlines future directions, emphasizing the importance of tailored, evidence-based approaches to preserve cardiovascular health and athletic longevity in this unique population.

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Publication Details

Journal
European Journal of Preventive Cardiology
Published
2025-09-22
DOI
https://doi.org/10.1093/eurjpc/zwaf607
Primary Topic
Cardiovascular Effects of Exercise
Type
article
Field-Weighted Citation Impact
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article

Fit but not immune from the risk: the hidden burden of dyslipidemia in elite athletes

Lorenzo Buzzelli, Pietro Lavisci, Michele Rizzi, Enrico Bernardo Loddo et al.
European Journal of Preventive Cardiology
Cardiovascular Effects of Exercise
article

Fit but not immune from the risk: the hidden burden of dyslipidemia in elite athletes

Lorenzo Buzzelli, Pietro Lavisci, Michele Rizzi, Enrico Bernardo Loddo, Maria Rosaria Squeo, Maurizio Volterrani, Camilla Calandri, Armando Ferrera, Raffaella Mistrulli, Barbara Sposato, Mihail Celeski, Jacek Kowalczyk, Giuseppe Di Gioia, Simone Crotta, Pietro Jansiti, Virginia Desiderio
article en

Abstract

Elite athletes are widely perceived to possess exceptional cardiovascular health due to their high levels of physical activity. However, emerging evidence suggests that among the established cardiovascular risk factors, dyslipidemia remains prevalent and frequently under-recognized in this population. Despite their athletic status, elite competitors, including Olympic and Paralympic athletes, may exhibit lipid abnormalities influenced by a complex interplay of factors such as sport type, training intensity, gender, ethnicity and disability status. This review aims to provide a comprehensive overview of dyslipidemia in elite athletes, exploring its prevalence, contributing physiological and lifestyle factors, clinical consequences and current approaches to assessment and management. Special attention is given to population-specific considerations, including gender, sport type and ethnicity. The limitations of general population cardiovascular risk scores in this context are discussed, with a focus on the need for athlete-specific tools such as the proposed "Lipid Athlete Score." Management strategies, ranging from lifestyle modification to the cautious use of pharmacologic agents and emerging nutraceutical interventions, are critically evaluated. Finally, the review highlights gaps in current research and outlines future directions, emphasizing the importance of tailored, evidence-based approaches to preserve cardiovascular health and athletic longevity in this unique population.

European Journal of Preventive Cardiology
University of Rome Tor Vergata (IT), Vita-Salute San Raffaele University (IT), University of Milan (IT), University of Ferrara (IT), Foro Italico University of Rome (IT), IRCCS Ospedale San Raffaele (IT), Campus Bio Medico University Hospital (IT), Institute of Sports Medicine and Science (JP), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT), Sapienza University of Rome (IT), University of Palermo (IT)
Openalex Percentile: Top 61%
Cardiovascular Effects of Exercise
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