Novel radiation-derived gene blueprint stratifying patients with breast cancer

To put it briefly, a strong efficient risk model was created to forecast prognosis, TME features, reactions to immunotherapy targeted medications in BRCA. This might lead to new understandings of individualized accurate treatment approaches. To facilitate clinical application, we have developed an R package and Excel-based calculator tool that enables clinicians to easily calculate patient risk scores using the 8-gene signature. These tools, along with detailed usage instructions, are freely available in the supplementary materials and GitHub repository.

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Publication Details

Journal
Discover Oncology
Published
2025-09-22
DOI
https://doi.org/10.1007/s12672-025-03549-1
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Novel radiation-derived gene blueprint stratifying patients with breast cancer

Hao Zhang, Enyi qiu, Shi Dong, H. T. LIN
Discover Oncology
Cancer Genomics and Diagnostics
article

Novel radiation-derived gene blueprint stratifying patients with breast cancer

Hao Zhang, Enyi qiu, Shi Dong, H. T. LIN
article en

Abstract

To put it briefly, a strong efficient risk model was created to forecast prognosis, TME features, reactions to immunotherapy targeted medications in BRCA. This might lead to new understandings of individualized accurate treatment approaches. To facilitate clinical application, we have developed an R package and Excel-based calculator tool that enables clinicians to easily calculate patient risk scores using the 8-gene signature. These tools, along with detailed usage instructions, are freely available in the supplementary materials and GitHub repository.

Discover OncologyVol. 16(1)
Wenzhou Central Hospital (CN)
Openalex Percentile: Top 69%
Cancer Genomics and Diagnostics
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