Comparative Effects of Repeated Ketamine Infusion Versus Intranasal Esketamine in Patients With Treatment-Resistant Depression
<b>Conclusion:</b> In this naturalistic sample of patients with similarly severe TRD treated in a ketamine subspecialty service over a 4-5-week induction period, treatment with IV racemic ketamine was associated with a more rapid response and greater overall efficacy than treatment with IN esketamine.
Authors
- Danika Dai
- Robert Meisner
- Paula Bolton
- Violeta Valdivia
- Courtney Miller (ORCID: https://orcid.org/0000-0002-5297-4523)
- Amanda Sedgewick
- Shuang Li (ORCID: https://orcid.org/0000-0002-3970-1061)
- Brian Boyle (ORCID: https://orcid.org/0000-0002-6882-1679)
- Steve Seiner
Institutions
- Harvard University (US)
- McLean Hospital (US)
Publication Details
- Journal
- The Journal of Clinical Psychiatry
- Published
- 2025-09-22
- DOI
- https://doi.org/10.4088/jcp.25m15789
- Citations
- 1
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 1.39