Aripiprazole or Bupropion Augmentation Versus Switching to Bupropion in Treatment-Resistant Depression
<b>Conclusion:</b> In our model, C-BUP better balanced efficacy and tolerability in TRD in adults under 85 years than did S-BUP or A-ARI. A-ARI was least-preferred in overweight adults. These results may inform shared decision-making and clinical guidelines.
Authors
- Philip S. Wang (ORCID: https://orcid.org/0009-0001-4227-5593)
- Jagpreet Chhatwal (ORCID: https://orcid.org/0000-0001-8741-4430)
- Rick H. Hoyle (ORCID: https://orcid.org/0000-0003-0900-2814)
- Eric L. Ross (ORCID: https://orcid.org/0000-0002-6025-2010)
- Chris J. Kennedy (ORCID: https://orcid.org/0000-0001-7444-2766)
- Jordan W. Smoller
- Matthew Meyerson (ORCID: https://orcid.org/0000-0003-1757-1451)
Institutions
- University of Vermont (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Duke University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- The Journal of Clinical Psychiatry
- Published
- 2025-09-22
- DOI
- https://doi.org/10.4088/jcp.25m15863
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00