Early Screening for Developmental Dysplasia of the Hip: Sonographic Reference Values, Risk Factors, and Treatment Considerations

Developmental dysplasia of the hip (DDH) is a common neonatal musculoskeletal disorder. In Germany, sonographic screening is recommended at 1-10 days of life for neonates with specific risk factors. This study aims to determine reference values for early sonographic screening and to evaluate associated risk factors. Between 2007 and 2022, 3383 neonates (6766 hips) underwent hip ultrasound according to Graf. Of these, 967 neonates were screened universally (2007-2015) and 1900 based on predefined risk factors (2015-2022). DDH was defined as ≥type IIc, according to Graf. A subgroup of 20 neonates with borderline alpha angles (51-52°) was followed up after 3-6 weeks. The mean alpha angle was 61.2° ± 5.3° (range 50.5-71.9°), and beta angle 70.8° ± 8.6° (range 53.6-88.0°). DDH prevalence was 2.5% in the universal and 3.2% in the risk-based cohort (<i>p</i> = 0.350). Logistic regression revealed associations with abnormal birth presentation (OR = 3.09, <i>p</i> < 0.001) and female sex (OR = 3.77, <i>p</i> < 0.001), not with Cesarean section or familial predisposition. In the follow-up subgroup, all hips showed a sufficient maturation to an alpha angle of 61.0° (range 57-66°). This study provides reference values for early DDH screening and confirms abnormal birth presentation and female sex as relevant risk factors.

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Publication Details

Journal
International Journal of Neonatal Screening
Published
2025-09-19
DOI
https://doi.org/10.3390/ijns11030081
Primary Topic
Hip disorders and treatments
Type
article
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article

Early Screening for Developmental Dysplasia of the Hip: Sonographic Reference Values, Risk Factors, and Treatment Considerations

Henning Tretow, Gregor Toporowski, Georg Gosheger, Bjoern Vogt et al.
International Journal of Neonatal Screening
Hip disorders and treatments
article

Early Screening for Developmental Dysplasia of the Hip: Sonographic Reference Values, Risk Factors, and Treatment Considerations

Henning Tretow, Gregor Toporowski, Georg Gosheger, Bjoern Vogt, Adrien Frommer, Andrea Laufer, Robert Roedl, Stella S. Tureck
article en

Abstract

Developmental dysplasia of the hip (DDH) is a common neonatal musculoskeletal disorder. In Germany, sonographic screening is recommended at 1-10 days of life for neonates with specific risk factors. This study aims to determine reference values for early sonographic screening and to evaluate associated risk factors. Between 2007 and 2022, 3383 neonates (6766 hips) underwent hip ultrasound according to Graf. Of these, 967 neonates were screened universally (2007-2015) and 1900 based on predefined risk factors (2015-2022). DDH was defined as ≥type IIc, according to Graf. A subgroup of 20 neonates with borderline alpha angles (51-52°) was followed up after 3-6 weeks. The mean alpha angle was 61.2° ± 5.3° (range 50.5-71.9°), and beta angle 70.8° ± 8.6° (range 53.6-88.0°). DDH prevalence was 2.5% in the universal and 3.2% in the risk-based cohort (<i>p</i> = 0.350). Logistic regression revealed associations with abnormal birth presentation (OR = 3.09, <i>p</i> < 0.001) and female sex (OR = 3.77, <i>p</i> < 0.001), not with Cesarean section or familial predisposition. In the follow-up subgroup, all hips showed a sufficient maturation to an alpha angle of 61.0° (range 57-66°). This study provides reference values for early DDH screening and confirms abnormal birth presentation and female sex as relevant risk factors.

International Journal of Neonatal ScreeningVol. 11(3)
University Hospital Münster (DE)
Openalex Percentile: Top 59%
Hip disorders and treatments
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