Acceptance of human papillomavirus vaccination and factors among mothers of 14 year old daughters Mattu Ethiopia: a cross-sectional study 2023

Background: Cervical cancer is a leading cause of mortality among women globally, with over one million cases attributed to human papillomavirus (HPV) types 16 and 18. In developing countries, including Ethiopia, cervical cancer ranks second in incidence and mortality, affecting approximately 6,294 women annually. This study aimed to assess the acceptance of HPV vaccination and identify associated factors among mothers/parents of 14-year-old daughters in Mattu Town, Oromia Regional State, Ethiopia, in 2023. Methods: A community-based cross-sectional study was conducted from March to April 2023, involving 430 mothers/parents selected through systematic random sampling. Data were collected using a pretested questionnaire and analyzed using SPSS version 26. Results: Out of 428 respondents (99% response rate), 80.6% (95% CI: 78.6-83.7) accepted HPV vaccination for their daughters. Acceptance was significantly associated with prior information exposure (AOR=3.0, 95% CI: 1.6-5.5), good knowledge of cervical cancer (AOR=4.0, 95% CI: 2.3-7.0), and a positive attitude towards vaccination (AOR=4.3, 95% CI: 2.7-7.5). Conclusions: Over three-fourths of parents are open to vaccinating their daughters against HPV, influenced by their knowledge and attitudes. To increase vaccine acceptance, promote community education and behavior change through ongoing health programs in schools, community centers, and media. Key players include the Mattu Town health office, schools, and NGOs.