A Lumped Parameter Modelling Study of Leukoaraiosis Suggests Its Vascular Pathophysiology May Be Similar to Normal-Pressure Hydrocephalus

The model suggests that the vascular physiology of LA maybe similar to NPH. A common pathophysiology is discussed based on a pulsation-induced increase in the venous outflow resistance.

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Publication Details

Journal
Brain Sciences
Published
2025-09-22
DOI
https://doi.org/10.3390/brainsci15091023
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
0.00
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article

A Lumped Parameter Modelling Study of Leukoaraiosis Suggests Its Vascular Pathophysiology May Be Similar to Normal-Pressure Hydrocephalus

Alexander Robert Bateman, Grant A. Bateman
Brain Sciences
Traumatic Brain Injury and Neurovascular Disturbances
article

A Lumped Parameter Modelling Study of Leukoaraiosis Suggests Its Vascular Pathophysiology May Be Similar to Normal-Pressure Hydrocephalus

Alexander Robert Bateman, Grant A. Bateman
article en

Abstract

The model suggests that the vascular physiology of LA maybe similar to NPH. A common pathophysiology is discussed based on a pulsation-induced increase in the venous outflow resistance.

Brain SciencesVol. 15(9)
John Hunter Hospital (AU), University of Newcastle Australia (AU)
Openalex Percentile: Top 63%
Traumatic Brain Injury and Neurovascular Disturbances
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