Development of a functional sarcopenia model utilizing a microcantilever microphysiological system as a phenotypic disease model
Development of the first defined in vitro functional model of sarcopenia on a microcantilever platform. This study recapitulates physiological signatures of disease progression characterized by loss of muscle mass and function and an increase in reactive oxygen species.
Authors
- Himanshi Jangir
- Russell Emmons (ORCID: https://orcid.org/0000-0002-3322-9835)
- Leandro Gallo
Institutions
- University of Central Florida (US)
- Hesperos (United States) (US)
Publication Details
- Journal
- In vitro models
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1007/s44164-025-00092-9
- Primary Topic
- Muscle activation and electromyography studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00