Biofilm maturation in carbapenem-resistant Pseudomonas aeruginosa is regulated by the sRNA PA213 and its corresponding encoded small protein
PA213 functions as a bifunctional sRNA-peptide regulator that promotes CRPA biofilm maturation via non-coding and protein-mediated mechanisms, offering new insights into hypoxia-responsive biofilm regulation and antimicrobial resistance evolution.
Authors
- Yongli Song (ORCID: https://orcid.org/0000-0003-2231-2438)
- Jie Li (ORCID: https://orcid.org/0000-0003-0973-8645)
- Yating Zhang (ORCID: https://orcid.org/0000-0003-2860-7464)
- Lingge Su
- Shuang Qin (ORCID: https://orcid.org/0000-0001-9264-6850)
- Chunyan Wu (ORCID: https://orcid.org/0000-0002-1511-4903)
- Guibo Song
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- International Journal of Antimicrobial Agents
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1016/j.ijantimicag.2025.107625
- Citations
- 2
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 1.61