Development of a genetically encoded melanocortin sensor for high sensitivity in vivo imaging
FLARE<sub>MC</sub> enables the study of melanocortin system in cultured cells and in vivo. This first of its class highly sensitive melanocortin sensor will serve as a valuable tool to advance our understanding of the complex dynamics governing melanocortin-dependent appetite regulation and related processes in the brain.
Authors
- Yoon Namkung (ORCID: https://orcid.org/0000-0002-3085-2066)
- Paul V. Sabatini (ORCID: https://orcid.org/0000-0001-6613-566X)
- Maia V. Kokoeva (ORCID: https://orcid.org/0000-0002-8029-4525)
- João Henrique Vieira Pedroso
- Tal Slutzki
- Xiaohong Liu (ORCID: https://orcid.org/0000-0002-5420-2391)
- Stéphane A. Laporte (ORCID: https://orcid.org/0000-0002-0633-543X)
Institutions
- McGill University Health Centre (CA)
- McGill University (CA)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.molmet.2025.102254
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.00