Changes in the Streptococcus pneumoniae population responsible for invasive disease of young children after the implementation of conjugated vaccines in the National Immunization Program in Poland
In the first three years after the introduction of the PCV10 into the Polish NIP significant reduction in the prevalence of PCV10-VTs was observed. Molecular characterization of the studied population allowed us to link the observed changes in the GPSC prevalence, with a decrease of infections caused by multi-drug resistant pneumococci and those with higher virulence associated with the presence of pili. The consistent evolution of S. pneumoniae influenced by population-based vaccinations, requires continuous surveillance.
Authors
- Marlena Kiedrowska (ORCID: https://orcid.org/0000-0003-2318-3375)
- Anna Skoczyńska (ORCID: https://orcid.org/0000-0002-2247-830X)
- Patrycja Ronkiewicz (ORCID: https://orcid.org/0000-0003-4427-5076)
- Ewa Sadowy (ORCID: https://orcid.org/0000-0003-0284-6440)
- Waleria Hryniewicz (ORCID: https://orcid.org/0000-0002-3651-9790)
- Alicja Kuch (ORCID: https://orcid.org/0000-0001-5416-1422)
- David Litt (ORCID: https://orcid.org/0000-0002-9215-0553)
- Izabela Wróbel-Pawelczyk (ORCID: https://orcid.org/0000-0002-4726-5984)
- Natalie Groves (ORCID: https://orcid.org/0000-0002-3832-3484)
- Agnieszka Gołębiewska (ORCID: https://orcid.org/0000-0002-9662-8243)
- K. Błaszczyk
Institutions
- Public Health England (GB)
- Narodowy Instytut Leków (PL)
Publication Details
- Journal
- Vaccine
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127759
- Citations
- 1
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.35