Developing and validating an elderly brain template: A comprehensive comparison with MNI152 for age-specific neuroimaging analyses
The Elderly template more accurately reflects older age-specific morphological changes and enhances spatial normalization accuracy, compared with the MNI152 template. This improvement suggests advancements in age-specific analyses and neurodegenerative disease research, enabling clinical applications.
Authors
- Genko Oyama (ORCID: https://orcid.org/0000-0001-7985-5367)
- Kazumichi Ota (ORCID: https://orcid.org/0000-0002-5440-4663)
- Yoshihiko Nakazato
Institutions
- Saitama Medical University (JP)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121473
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00