The protective role of IL-17C in oral squamous cell carcinoma
IL-17C appears to play a protective role in some OSCC cells. While this study indicates the potential of using IL-17C as a therapeutic candidate for OSCC patients, its relatively mild and selective effect suggests it may be more effective as part of a combination therapy.
Authors
- Sami Kilpinen (ORCID: https://orcid.org/0000-0003-3444-2539)
- Maija Risteli (ORCID: https://orcid.org/0000-0002-2316-7554)
- Jaakko Suominen (ORCID: https://orcid.org/0000-0003-1352-7699)
- Aruni Ratnayake (ORCID: https://orcid.org/0000-0002-2724-019X)
- Tuulia Onali
- Wafa Wahbi (ORCID: https://orcid.org/0000-0001-9416-5196)
- Tuula Anneli Salo (ORCID: https://orcid.org/0000-0001-6039-0088)
- Ahmed Al‐Samadi (ORCID: https://orcid.org/0000-0003-1938-2136)
- Martina Giacomini (ORCID: https://orcid.org/0009-0007-7548-6438)
- Katja Korelin
- Zivile Giedraityte
Institutions
- University of Helsinki (FI)
- University of Eastern Finland (FI)
- Oulu University Hospital (FI)
- Helsinki University Hospital (FI)
- Finland University (FI)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.tranon.2025.102541
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00