Sclerosing mesenteritis in a dog ( <i>Canis lupus familiaris</i> )

Abstract Sclerosing mesenteritis is an idiopathic inflammatory disease affecting the abdominal cavity. A 10‐year‐old spayed female Pembroke Welsh Corgi was referred to our animal hospital with a 7‐day history of anorexia, vomiting, dyschezia and an abdominal mass. Diagnostic imaging revealed a mid‐abdominal mass with a thickened surrounding mesentery. Histopathological examination of an incisional biopsy specimen, obtained through exploratory laparotomy, indicated pyogenic granulomatous panniculitis. No evident infections or foreign bodies were detected in the abdominal cavity. Based on imaging and histopathological findings, the mass was diagnosed as sclerosing mesenteritis. The dog received prednisolone at an anti‐inflammatory dose, resulting in the complete resolution of the clinical signs and the mass. Prednisolone was tapered over 5 months and then discontinued. The dog remained healthy after treatment. To our knowledge, this is the first documented case of canine sclerosing mesenteritis.