SPP1+ macrophages polarized by lactate confer the progression of hypoxic adaptive tumor cells in brain
The interrelationship between hypoxic adaptive tumor cells and macrophages in the brain highlights the possibility of SPP1+ macrophage-based microenvironment remodeling in brain tumor therapy.
Authors
- Qianming Yao
- Hongfan Liao (ORCID: https://orcid.org/0000-0002-0574-6421)
- Xianfeng Yu (ORCID: https://orcid.org/0009-0008-1666-4545)
- Jianlei Zhang (ORCID: https://orcid.org/0000-0002-9932-9265)
- Yabing Cao (ORCID: https://orcid.org/0000-0003-1641-6716)
- Guopei Zheng (ORCID: https://orcid.org/0000-0002-4662-9993)
- Qiong Zhang (ORCID: https://orcid.org/0000-0001-5001-8434)
- Zhihui Li (ORCID: https://orcid.org/0000-0002-9872-7624)
- Jiang Yin
- Weina Fan (ORCID: https://orcid.org/0000-0003-4683-6121)
- Jing Dong (ORCID: https://orcid.org/0000-0002-3684-2432)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Kiang Wu Hospital (CN)
- Guangzhou Medical University Cancer Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1093/neuonc/noaf208
- Citations
- 3
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.81