Long-Term Outcomes and Clinical Factors Associated with Conventional Therapy Failure in Intestinal Behçet’s Disease: A Retrospective Cohort Study in Japan
Large ulcer size, PPI use, high CRP, and hematochezia are risk factors for CT failure. Anti-TNF-α agents are effective in patients with CT failure, and risk-based treatment strategies may improve disease control in patients with i-BD.
Authors
- Hiroto Kinoshita (ORCID: https://orcid.org/0000-0002-8179-6017)
- Sozaburo Ihara (ORCID: https://orcid.org/0000-0001-8495-2073)
- Junya Arai (ORCID: https://orcid.org/0000-0002-4905-7046)
- Mitsuhiro Fujishiro (ORCID: https://orcid.org/0000-0002-4074-1140)
- Haruka Tsuchiya (ORCID: https://orcid.org/0000-0002-2114-7656)
- Keishi Fujio (ORCID: https://orcid.org/0000-0001-7276-5254)
- Yumi Tsuchida (ORCID: https://orcid.org/0000-0003-3236-6157)
- Yoku Hayakawa (ORCID: https://orcid.org/0000-0002-3988-2499)
- Nobumi Suzuki (ORCID: https://orcid.org/0000-0002-8402-4530)
- Ken Kurokawa (ORCID: https://orcid.org/0000-0001-8389-3315)
- Mayo Tsuboi
- Keita Murakami (ORCID: https://orcid.org/0009-0005-1961-1850)
Institutions
- Bunkyo University (JP)
- The Institute of Medical Science, Asahi Life Foundation (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Digestion
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1159/000548559
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00