Clinical Presentation, Treatment Patterns, Burden of Disease, and the Association of Proteinuria with Clinical Outcomes in C3 Glomerulopathy and Primary Immune Complex Membranoproliferative Glomerulonephritis: A Systematic Review
This SLR provides insights into C3G and primary IC-MPGN, emphasizing the need for new targeted and effective treatments. Proteinuria was identified to be an acceptable marker in assessing the efficacy of treatments on long-term kidney outcomes.
Authors
- Carly Rich (ORCID: https://orcid.org/0000-0003-4717-5855)
- Luis López Lázaro (ORCID: https://orcid.org/0000-0003-0620-6133)
- Lucía Quintana‐Gallardo (ORCID: https://orcid.org/0000-0002-1897-3535)
- Vikte Lionikaite (ORCID: https://orcid.org/0000-0003-1605-3046)
- Fernando Caravaca‐Fontán (ORCID: https://orcid.org/0000-0002-5830-9663)
- Regina Horneff
- Matthew C. Pickering (ORCID: https://orcid.org/0000-0002-1153-0192)
- Fádi Fakhouri (ORCID: https://orcid.org/0000-0001-5390-8002)
- Alison E. Baird
Institutions
- Oxford Instruments (United Kingdom) (GB)
- Research Institute Hospital 12 de Octubre (ES)
- Swedish Orphan Biovitrum (Sweden) (SE)
- Imperial College London (GB)
- University of Lausanne (CH)
Publication Details
- Journal
- The Nephron journals/Nephron journals
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1159/000548245
- Citations
- 1
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80