Long-term antitumour effects of pasireotide in acromegaly
Pasireotide appears to induce durable cystic degeneration in somatotroph tumours, with evidence suggesting sustained antitumor effects that may extend beyond treatment discontinuation. These findings support its potential for a broader therapeutic role, warranting validation in future prospective studies.
Authors
- Julie Celine Refardt (ORCID: https://orcid.org/0000-0002-3040-4685)
- Eskeatnaf Mulugeta (ORCID: https://orcid.org/0000-0003-4045-4835)
- Sebastian Neggers (ORCID: https://orcid.org/0000-0002-7698-0282)
- Romy van der Groef (ORCID: https://orcid.org/0000-0002-3168-8982)
- Sophie E. M. Veldhuijzen van Zanten (ORCID: https://orcid.org/0000-0002-3888-0977)
- Denise van Beekveld
Institutions
- Erasmus MC (NL)
- Erasmus MC Cancer Institute (NL)
- Rotterdam University of Applied Sciences (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-09-20
- DOI
- https://doi.org/10.1093/ejendo/lvaf194
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00