SIRT3 inhibits fibroblast-like synoviocytes activation in rheumatoid arthritis through delactylation of H3K18
SIRT3 suppresses RA progression by delactylating H3K18. These findings may pave the way for novel lactylation-targeted therapies in RA.
Authors
- Jianxiong Zheng
- Jinyue Lu
- Min Tan (ORCID: https://orcid.org/0000-0002-1986-8438)
- Yanling Yu (ORCID: https://orcid.org/0000-0003-1477-7382)
- Jing Mao (ORCID: https://orcid.org/0000-0001-6353-9992)
- Jun Li
- Hongxia Wang (ORCID: https://orcid.org/0000-0001-8779-1201)
- Chunhua Liu
- Haili Shen (ORCID: https://orcid.org/0000-0002-1618-6765)
- Jiayao Hao
Institutions
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1093/rheumatology/keaf497
- Citations
- 4
- Primary Topic
- Magnolia and Illicium research
- Type
- article
- Field-Weighted Citation Impact
- 4.10