Association of nociplastic pain with executive function decline in a longitudinal cohort of middle-age adults: a prospective cohort study
Nociplastic pain severity is associated with worse executive function but reassuringly does not suggest worse cognitive decline. Abnormal sleep duration, anxiety, and pain intensity are highlighted as potential intervention targets.
Authors
- Xin-You Tai
- Irene Tracey (ORCID: https://orcid.org/0000-0003-4134-6115)
- Thomas E. Nichols (ORCID: https://orcid.org/0000-0002-4516-5103)
- Trishna Rathod‐Mistry (ORCID: https://orcid.org/0000-0002-6369-4746)
- Eoin Kelleher (ORCID: https://orcid.org/0000-0003-2025-5556)
- Andrew Schrepf (ORCID: https://orcid.org/0000-0003-4291-0320)
- Anushka Soni (ORCID: https://orcid.org/0000-0002-7831-4208)
Institutions
- Nuffield Orthopaedic Centre (GB)
- University of Oxford (GB)
- Pain and Headache Center (US)
- Center for Pain and the Brain (US)
Publication Details
- Journal
- British Journal of Anaesthesia
- Published
- 2025-09-20
- DOI
- https://doi.org/10.1016/j.bja.2025.08.002
- Citations
- 1
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Pfizer
- Wellcome Trust
- National Institute for Health and Care Research
- Department of Health and Social Care