Efficacy of combined clazosentan and cilostazol therapy for cerebral vasospasm after subarachnoid hemorrhage: a retrospective multicenter registry study
The combination of clazosentan and cilostazol may reduce the incidence of DCI, although its impact on functional outcomes remains unclear. Further research is warranted to explore effective pharmacological strategies for improving the prognosis of aSAH.
Authors
- Shinji Shimato
- Takashi Yamanouchi (ORCID: https://orcid.org/0000-0001-6803-1901)
- Nobuhiko Mizutani
- Ikuya Takeuchi (ORCID: https://orcid.org/0009-0008-5620-1617)
- Ryuta Saito (ORCID: https://orcid.org/0000-0002-2484-1360)
- Masahiro Nishihori (ORCID: https://orcid.org/0000-0003-1645-0738)
- Toshinori Hasegawa (ORCID: https://orcid.org/0000-0001-6535-0229)
- Takashi Izumi (ORCID: https://orcid.org/0000-0003-2898-3371)
- Satoshi Maesawa (ORCID: https://orcid.org/0000-0001-7518-0171)
- Takeshi Okada (ORCID: https://orcid.org/0000-0003-2916-9398)
- Kiyo Nakabayashi
- Shigemasa Hayashi
- Shinsuke Muraoka (ORCID: https://orcid.org/0000-0003-4225-110X)
- T Tsukada (ORCID: https://orcid.org/0000-0002-0332-2596)
- Fumie Kinoshita (ORCID: https://orcid.org/0000-0002-3008-0748)
- Ryotaro Sugita
- Takeshi Kinkori
- Shunsaku Goto (ORCID: https://orcid.org/0000-0003-3177-7691)
- Hideki Maki
- Osamu Suzuki
- Shuntaro Takasu
- Masashige Iwasaki
- Takumi Asai
- T Kano
- Kazuki Ishii (ORCID: https://orcid.org/0009-0006-9581-6783)
- Hisashi Hatano
- Shigekazu Nakamura
Institutions
- Nagoya University Hospital (JP)
- Nagoya Ekisaikai Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-09-20
- DOI
- https://doi.org/10.3171/2025.5.jns243007
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00