Langerhans Cell Histiocytosis in the central nervous system, cranial and spinal bones: imaging features

Imaging plays an essential role in properly diagnosing, guiding biopsy and monitoring treatment. Computed tomography (CT) is particularly helpful for evaluating bone involvement, while magnetic resonance imaging (MRI) is preferred for assessing parenchymal brain and meningeal lesions. The disease can present in either tumoral or neurodegenerative forms, manifesting with varied symptoms depending on the affected region.

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Publication Details

Journal
Expert Review of Clinical Immunology
Published
2025-09-20
DOI
https://doi.org/10.1080/1744666x.2025.2564827
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Langerhans Cell Histiocytosis in the central nervous system, cranial and spinal bones: imaging features

Nina Ventura, Diogo Goulart Corrêa, Luiz Celso Hygino da Cruz Júnior, Simone Rachid de Souza et al.
Expert Review of Clinical Immunology
Histiocytic Disorders and Treatments
article

Langerhans Cell Histiocytosis in the central nervous system, cranial and spinal bones: imaging features

Nina Ventura, Diogo Goulart Corrêa, Luiz Celso Hygino da Cruz Júnior, Simone Rachid de Souza, Tomás de Andrade Lourenção Freddi, Luciane dos Santos Oliveira, Gabriela Amaral Ribas, Lara Hemerly De Mori, Waldir Heringer Maymone
article en

Abstract

Imaging plays an essential role in properly diagnosing, guiding biopsy and monitoring treatment. Computed tomography (CT) is particularly helpful for evaluating bone involvement, while magnetic resonance imaging (MRI) is preferred for assessing parenchymal brain and meningeal lesions. The disease can present in either tumoral or neurodegenerative forms, manifesting with varied symptoms depending on the affected region.

Expert Review of Clinical ImmunologyVol. 21(10)
Universidade Federal do Rio de Janeiro (BR), United Nations Industrial Development Organization (AT), Universidade do Estado do Rio de Janeiro (BR), Centrus Diagnósticos por Imagem (BR), Elixir Medical (United States) (US)
Openalex Percentile: Top 68%
Histiocytic Disorders and Treatments
DOISourceOpenAlex
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Langerhans Cell Histiocytosis in the central nervous system, cranial and spinal bones: imaging features — Nina Ventura, Diogo Goulart Corrêa, et al. · Expert Review of Clinical Immunology (2025) | TGRS Research Map | TGRS