Feasibility of randomisation to radical prostatectomy or standard care in patients with metastatic prostate cancer
Randomising men with newly diagnosed mPCa to RP plus SOC vs SOC alone proved challenging in this Belgian trial. Major barriers to recruitment included limited surgical eligibility and patient refusal. Targeted recruitment strategies or alternative trial designs should be considered.
Authors
- Pieter Uvin
- Wouter Everaerts (ORCID: https://orcid.org/0000-0002-3157-7115)
- Wesley Verla (ORCID: https://orcid.org/0000-0001-5755-7078)
- Filip Ameye (ORCID: https://orcid.org/0000-0001-7445-0803)
- Charles Van Praet (ORCID: https://orcid.org/0000-0002-4467-0829)
- Valérie Fonteyne (ORCID: https://orcid.org/0000-0001-6724-1595)
- Karen Fransis
- Thomas van Erps
- Piet Ost (ORCID: https://orcid.org/0000-0002-2203-4848)
- Nicolaas Lumen (ORCID: https://orcid.org/0000-0003-1242-3644)
- Lies Van den Eynde (ORCID: https://orcid.org/0009-0008-3664-9174)
Institutions
- Universitair Ziekenhuis Leuven (BE)
- Ghent University Hospital (BE)
- Ghent University (BE)
- Antwerp University Hospital (BE)
- AZ Sint-Jan (BE)
- AZ Maria Middelares (BE)
- KU Leuven (BE)
Publication Details
- Journal
- British Journal of Urology
- Published
- 2025-09-20
- DOI
- https://doi.org/10.1111/bju.70006
- Citations
- 2
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Fonds Wetenschappelijk Onderzoek
- Kom op tegen Kanker
- Vlaamse regering
- Stand Up To Cancer