Clinical evaluation of dynamic [18F]FDG PET imaging to distinguish infection from inflammation in fracture-related infections
This proof-of-concept study demonstrates that dynamic [<sup>18</sup>F]FDG PET/CT using TACs can distinguish infection from inflammation in patients with suspected FRI, with high diagnostic accuracy observed, and suggesting a potential advantage over standard imaging. Larger-scale studies are needed to validate these results and explore the full clinical potential of dynamic imaging in infection management.
Authors
- Riemer H. J. A. Slart (ORCID: https://orcid.org/0000-0002-5565-1164)
- Joyce van Sluis (ORCID: https://orcid.org/0000-0003-1908-4518)
- Johannes H. van Snick (ORCID: https://orcid.org/0009-0008-0417-1823)
- Frank F. A. IJpma (ORCID: https://orcid.org/0000-0002-9420-2732)
- Andor W.J.M. Glaudemans (ORCID: https://orcid.org/0000-0001-8081-0641)
- Nick D. van Rijsewijk (ORCID: https://orcid.org/0000-0001-7132-9792)
- Marjan Wouthuyzen‐Bakker (ORCID: https://orcid.org/0000-0001-7866-2467)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- University of Twente (NL)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-09-20
- DOI
- https://doi.org/10.1007/s00259-025-07563-x
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01