Precision Neuroscience’s Layer 7 Cortical Interface: Technical Design, Surgical Integration, and Clinical Outcomes

The Layer 7 Cortical Interface by Precision Neuroscience is a next-generation brain–computer interface (BCI) that offers high-resolution neural access through a minimally invasive, subdural approach. The system eliminates the need for craniotomy while maintaining submillimeter spatial resolution by utilizing ultra-thin, flexible electrode arrays and a proprietary cranial micro-slit insertion method. Each array contains up to 1,024 platinum electrodes and integrates with a compact, real-time signal acquisition platform capable of recording and stimulation. This bidirectional architecture supports closed-loop applications such as motor decoding, sensory feedback, and neuromodulation. Clinical deployments across major U.S. institutions have validated its safety, stability, and signal fidelity in intraoperative and intensive care settings. With demonstrated performance in mapping eloquent cortex, extended monitoring, and targeted stimulation, the Layer 7 system presents a scalable, patient-centric alternative to traditional BCIs—aligning engineering innovation with routine clinical workflows.