Preparation, Pharmaceutico-analysis and Dosage Standardisation of Priyangvadi Syrup for Common Childhood Ailments

Introduction: Priyangvadi Kalka, a traditional herbal paste, is mentioned in Bhaishajya Ratnawali, specifically in the Balrogadhikar Adhyaya, which is dedicated to child health and ailments. Traditionally combined with honey, Priyangvadi Kalka is used to treat diarrhea, vomiting, fever, and dehydration-induced thirst in children, given its cooling, antipyretic, antiemetic, and antibacterial properties. However, its bitter taste, short shelf life, and paste form make it less suitable for children. Converting this paste into a sugar syrup would enhance its palatability, shelf life, and efficacy. Aim: The aim of this study is the modification, preparation, and standardisation of Priyangvadi syrup and to study the pharmaceutico-analytical properties of the syrup. Materials and Methods: This pharmaceutico-analytical study was conducted between September 2023 and January 2024 at Mahatma Gandhi Ayurved College Hospital and Research Centre Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, Maharashtra, India. Relevant Ayurvedic texts and research on each ingredient were reviewed. Raw drugs were collected, authenticated, and then used to prepare the syrup following standardised methods. The preparation of the syrup, including packaging, was completed within three days. Pharmaceutical analysis was conducted to ensure safety for children. Results: The study successfully developed Priyangvadi syrup, characterised by its brown colour and sweet taste, and confirmed through analysis to be safe for pediatric use. The syrup form enhances palatability, stability, and ease of dosage calculation for children. It can remain effective for up to one year without requiring refrigeration. Conclusion: All the ingredients help balance doshas and exhibit antiemetic, antidiarrheal, antimicrobial properties while supporting digestion. Priyangvadi syrup can effectively treat vomiting, diarrhea, dehydration, and other gastrointestinal issues in young children, improving digestion without causing harm, thus reducing the need for suppressive medicines and antibiotics. The syrup form makes it palatable, stable, and suitable for children’s dosing.