Association of low shunt burden from PDA and adverse outcomes in premature infants
Prolonged exposure to low-volume PDA shunt was not associated with increased risk of death or abnormal respiratory outcome. Findings highlight the importance of redefining eligibility criteria for PDA trials, based on adjudication of shunt volume, to limit enrollment to patients with moderate- to high-volume shunts.
Authors
- Danielle R. Rios (ORCID: https://orcid.org/0000-0002-2766-9244)
- Christina Brandt (ORCID: https://orcid.org/0009-0003-9638-2700)
- Adrianne R. Bischoff (ORCID: https://orcid.org/0000-0001-9218-1301)
- Patrick J. McNamara (ORCID: https://orcid.org/0000-0001-7648-8872)
- Hatice Dilara Mat (ORCID: https://orcid.org/0009-0004-3467-8490)
Institutions
- University of Iowa (US)
Publication Details
- Journal
- Journal of Perinatology
- Published
- 2025-09-20
- DOI
- https://doi.org/10.1038/s41372-025-02437-4
- Citations
- 1
- Primary Topic
- Cardiovascular Conditions and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36