[18F]SiTATE PET for PRRT selection and monitoring metastatic tumors of the adrenal medulla and extra-adrenal paraganglia
In metastatic PPGL, [<sup>18</sup>F]SiTATE effectively visualizes tumor burden and supports patient selection and response assessment for PRRT. Notably, the data revealed a heterogenous response across PET-based, CT-based, and biochemical assessments. The underlying mechanisms of these discrepancies remain unclear and warrant further investigation.
Authors
- Christoph Josef Auernhammer (ORCID: https://orcid.org/0000-0001-8087-3722)
- Vera Wenter (ORCID: https://orcid.org/0000-0001-7385-5702)
- Maximilian Scheifele
- Christian Lottspeich (ORCID: https://orcid.org/0000-0002-1770-4392)
- Rudolf Alexander Werner (ORCID: https://orcid.org/0000-0003-3372-6046)
- Matthias Kroiß (ORCID: https://orcid.org/0000-0002-7628-3161)
- Friederike Völter (ORCID: https://orcid.org/0000-0001-6157-0363)
- Adrien Holzgreve (ORCID: https://orcid.org/0000-0002-9566-8438)
- Gabriel T. Sheikh (ORCID: https://orcid.org/0000-0002-7026-9203)
- Christine Spitzweg (ORCID: https://orcid.org/0000-0002-0413-9697)
- Michael Schöll (ORCID: https://orcid.org/0000-0001-7800-1781)
- Matthias K. Auer (ORCID: https://orcid.org/0000-0001-7153-8332)
- Svenja Nölting (ORCID: https://orcid.org/0000-0002-7064-590X)
- Simon Lindner (ORCID: https://orcid.org/0009-0007-4379-4436)
- Franz Josef Gildehaus (ORCID: https://orcid.org/0000-0002-6830-1817)
- Mathias J. Zacherl
- Sophie C. Kunte (ORCID: https://orcid.org/0009-0003-3175-952X)
Institutions
- Johns Hopkins University (US)
- University of Zurich (CH)
- University of Siegen (DE)
- Johns Hopkins Medicine (US)
- LMU Klinikum (DE)
- Technical University of Applied Sciences Würzburg-Schweinfurt (DE)
- University Hospital of Zurich (CH)
- Leopoldina Krankenhaus Schweinfurt (DE)
- SKF (Germany) (DE)
- Molecular Theranostics (United States) (US)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1007/s00259-025-07550-2
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00