High-Risk Human Papillomavirus Positive-Negative-Positive Infection Pattern Revealed Infection Below the Screening Test Cutoff
hrHPV positive-negative-positive infection patterns were rare in the authors' cohort. hrHPV DNA negativity with the Hybrid Capture 2 test was mainly explained by the presence of HPV below the assay cutoff. Therefore, the authors' study does not provide clear evidence of HPV latency but rather of subclinical infection with low viral load.
Authors
- Jean‐Luc Prétet (ORCID: https://orcid.org/0000-0002-8430-214X)
- C Bertin
- Quentin Lepiller (ORCID: https://orcid.org/0000-0003-2892-4216)
- Marie‐Paule Algros
- R. Ramanah (ORCID: https://orcid.org/0000-0001-9216-5133)
- Nolwen Di Domizio
Institutions
- Institut Pasteur (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Université Marie et Louis Pasteur (FR)
Publication Details
- Journal
- Journal of Lower Genital Tract Disease
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1097/lgt.0000000000000911
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00