Furmonertinib rechallenge for first-line third-generation EGFR TKI-resistant EGFR-mutant NSCLC: A retrospective propensity score-matched cohort study

Furmonertinib showed similar effectiveness and better safety compared with chemotherapy in NSCLC patients resistant to first-line third-generation EGFR TKIs. After matching, furmonertinib demonstrated numerically longer PFS than chemotherapy. Randomized controlled trials are warranted.

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Publication Details

Journal
Cancer Treatment and Research Communications
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ctarc.2025.101003
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Furmonertinib rechallenge for first-line third-generation EGFR TKI-resistant EGFR-mutant NSCLC: A retrospective propensity score-matched cohort study

Maolin Liu, Dilimulati Abulizi, Xi Chen, Xue Hou et al.
Cancer Treatment and Research Communications
Lung Cancer Treatments and Mutations
article

Furmonertinib rechallenge for first-line third-generation EGFR TKI-resistant EGFR-mutant NSCLC: A retrospective propensity score-matched cohort study

Maolin Liu, Dilimulati Abulizi, Xi Chen, Xue Hou, Siqing Liu, Jiaqi Zhao
article en

Abstract

Furmonertinib showed similar effectiveness and better safety compared with chemotherapy in NSCLC patients resistant to first-line third-generation EGFR TKIs. After matching, furmonertinib demonstrated numerically longer PFS than chemotherapy. Randomized controlled trials are warranted.

Cancer Treatment and Research CommunicationsVol. 45
Sun Yat-sen University (CN), Sun Yat-sen University Cancer Center (CN), State Key Laboratory of Oncology in South China
Openalex Percentile: Top 63%
Lung Cancer Treatments and Mutations
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