Cytokine-induced transcriptional changes in human neutrophils reveal immune regulatory plasticity
This work defines the differential gene expression patterns in neutrophils exposed to different regulatory cytokines. This is important in both increasing our understanding of the role of neutrophils in driving innate and adaptive immune responses and, importantly, for deconvoluting the neutrophil gene expression signatures observed in inflammatory diseases.
Authors
- Steven W. Edwards (ORCID: https://orcid.org/0000-0002-7074-0552)
- Huw B. Thomas (ORCID: https://orcid.org/0000-0001-9626-9706)
- Helen L. Wright (ORCID: https://orcid.org/0000-0003-0442-3134)
Institutions
- University of Liverpool (GB)
Publication Details
- Journal
- Discovery Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/discim/kyaf013
- Citations
- 4
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- Versus Arthritis
- Biotechnology and Biological Sciences Research Council