Experimental method to assess depth sensing limits of inelastic scattering measurements using spatial-offset Raman spectroscopy imaging
We showed the feasibility of using bilayer solid optical phantoms to create correlation curves between the optimal spatial offset for a desired probed depth given the optical properties of the top layer. The technique could facilitate the clinical translation of SORS measurements for tumor detection and margins assessment.
Authors
- Maroun Massabki
- Jean‐François Masson (ORCID: https://orcid.org/0000-0002-0101-0468)
- Patrick Orsini
- Guillaume Sheehy (ORCID: https://orcid.org/0000-0002-4721-6066)
- Hugo Tavera (ORCID: https://orcid.org/0000-0002-4973-8300)
- Marie‐Maude de Denus‐Baillargeon
- Frédéric Leblond (ORCID: https://orcid.org/0000-0002-8154-4952)
- Jacques Bismuth
Institutions
- Optech (Canada) (CA)
- Regroupement Québécois sur les Matériaux de Pointe (CA)
- Polytechnique Montréal (CA)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1117/1.jbo.30.s3.s34108
- Citations
- 1
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 1.63