Long-term outcomes of active surveillance after DOTATATE PET/MRI–confirmed gross total resection in WHO grade 2 meningioma

DOTATATE PET/MRI-confirmed GTR followed by active surveillance yielded significantly higher PFS compared to MRI-based GTR assessment in patients with WHO-2 meningioma. DOTATATE PET/MRI increases diagnostic certainty, enabling more accurate postoperative risk stratification and potentially avoiding unnecessary RT, supporting its integration into postoperative decision-making for WHO-2 meningioma.

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Publication Details

Journal
Neuro-Oncology Advances
Published
2025-01-01
DOI
https://doi.org/10.1093/noajnl/vdaf210
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Long-term outcomes of active surveillance after DOTATATE PET/MRI–confirmed gross total resection in WHO grade 2 meningioma

Benjamin Liechty, Kellen Vo Vu, Kathryn Beal, Rohan Ramakrishna et al.
Neuro-Oncology Advances
Meningioma and schwannoma management
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Long-term outcomes of active surveillance after DOTATATE PET/MRI–confirmed gross total resection in WHO grade 2 meningioma

Benjamin Liechty, Kellen Vo Vu, Kathryn Beal, Rohan Ramakrishna, Jana Ivanidze, Nicolas A. Karakatsanis, Michelle Roytman, Sadek A. Nehmeh, Kate Rosen, Sean H. Kim, Joseph R. Osborne, Rajiv Magge, Philip E. Stieg, Andrew Watson, Jonathan Knisely, Theodore H. Schwartz, Umberto Tosi, Arsalan Haghdel, Andrew Brandmaier, Se Jung Chang, Valentina Marulanda Corzo, Susan C. Pannullo, Arindam RoyChoudhury, Eaton Lin, Peter Pan, David J. Pisapia, Martin Zonenshayn, Hannah Gabrielle Otis, Peter Chernek
article en

Abstract

DOTATATE PET/MRI-confirmed GTR followed by active surveillance yielded significantly higher PFS compared to MRI-based GTR assessment in patients with WHO-2 meningioma. DOTATATE PET/MRI increases diagnostic certainty, enabling more accurate postoperative risk stratification and potentially avoiding unnecessary RT, supporting its integration into postoperative decision-making for WHO-2 meningioma.

Neuro-Oncology AdvancesVol. 7(1)
Cornell University (US), Mount Sinai Hospital (US), Neurological Surgery (US), Weill Cornell Medicine (US), Columbia University (US)
Openalex Percentile: Top 65%
Meningioma and schwannoma management
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