Hydroxychloroquine discontinuation in SLE: a retrospective cohort study with 3-year follow-up
50% of patients who discontinued HCQ flared within 2 years. Low C3 levels at baseline were associated with increased risk of flares. These findings suggest that flares are common soon after HCQ discontinuation, and low C3 may help identify patients at higher risk for disease reactivation after HCQ discontinuation.
Authors
- Eduardo Cardoso (ORCID: https://orcid.org/0000-0003-3353-2831)
- Vasileios C. Kyttaris (ORCID: https://orcid.org/0000-0001-7652-3826)
- Milena Delai (ORCID: https://orcid.org/0009-0003-9180-9170)
- Rachel Simon
Institutions
- Beth Israel Deaconess Medical Center (US)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1093/rheumatology/keaf498
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00