Evaluation of QIAreach QuantiFERON-TB lateral-flow nanoparticle fluorescence assay for TB infection diagnosis among TB household contacts in three high-burden settings
QIAreach demonstrated a moderate concordance against QFT-Plus among HHCs in three high-burden countries. Further work is needed to understand and improve its usability in high TB and low resource settings.
Authors
- Thobani Ntshiqa (ORCID: https://orcid.org/0000-0002-0752-3192)
- Don Mudzengi (ORCID: https://orcid.org/0000-0003-2759-3320)
- Kavindhran Velen (ORCID: https://orcid.org/0000-0001-8577-3915)
- Stacie Stender (ORCID: https://orcid.org/0000-0001-9719-358X)
- Tobias Chirwa (ORCID: https://orcid.org/0000-0003-4344-0842)
- Salome Charalambous (ORCID: https://orcid.org/0000-0001-7143-1009)
- Molebogeng Xheedha Rangaka (ORCID: https://orcid.org/0000-0001-9594-188X)
- Manthomeng Matete
- Yohhei Hamada (ORCID: https://orcid.org/0000-0002-9845-4267)
- Abisai Kisinda
- Issa Sabi (ORCID: https://orcid.org/0000-0002-1777-6572)
- Nyanda Elias Ntinginya (ORCID: https://orcid.org/0000-0002-1575-4521)
- Stefan Niemann
- Lilian Tina Minja (ORCID: https://orcid.org/0000-0002-9597-0207)
- Julieth Lalashowi (ORCID: https://orcid.org/0000-0002-6213-5213)
- Jeniffer Nagudi (ORCID: https://orcid.org/0000-0001-8838-9564)
- Lula Budiaki
- Malebo Mahlalela
- Knut Lönnroth (ORCID: https://orcid.org/0000-0001-5054-8240)
- Andrew Copas
- Viola Dreyer
- Lindiwe Tsope
- Akinlolu Fasanmi
Institutions
- University of the Witwatersrand (ZA)
- Karolinska Institutet (SE)
- Lesotho Planned Parenthood Association (LS)
- German Center for Infection Research (DE)
- Aurum Institute (ZA)
- Research Center Borstel - Leibniz Lung Center (DE)
- National Institute for Medical Research (TZ)
- University College London (GB)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1371/journal.pone.0332125
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00