Methylprednisolone plus MTX-based regime vs prednisone-based standard of care for GCA: a propensity score study
The combination IVMP/MTX with lower-dose prednisone is as effective as the SOC in inducing remission and preventing relapses in GCA. The IVMP/MTX scheme significantly reduces GC exposure and GC-associated adverse effects. IVMP/MTX could be a potential GC-sparing strategy, especially in patients with GCA at higher risk of GC toxicity.
Authors
- Georgina Espígol‐Frigolé (ORCID: https://orcid.org/0000-0002-8299-0209)
- Guillermo Ruiz‐Irastorza (ORCID: https://orcid.org/0000-0001-7788-1043)
- Ioana Ruiz‐Arruza
- Leonor Acha
- Adriana Soto-Peleteiro (ORCID: https://orcid.org/0000-0001-8959-8683)
- José Hernández‐Rodríguez (ORCID: https://orcid.org/0000-0002-2357-2015)
- Sergio Prieto‐González (ORCID: https://orcid.org/0000-0003-3179-597X)
- María C. Cid (ORCID: https://orcid.org/0000-0002-4730-0938)
- Halbert Hernández-Negrín
- Verónica Gómez‐Caverzaschi (ORCID: https://orcid.org/0000-0001-5242-6925)
- Borja de Miguel-Campo (ORCID: https://orcid.org/0000-0001-7105-9470)
- Olga Araújo (ORCID: https://orcid.org/0000-0003-1763-1880)
- Fátima Raad (ORCID: https://orcid.org/0009-0008-7923-5422)
- Marina Torio
Institutions
- University of the Basque Country (ES)
- BioCruces Health research Institute (ES)
- Hospital Universitario 12 De Octubre (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1093/rheumatology/keaf499
- Citations
- 2
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 3.04