Facilitators and barriers for completion of the diagnostic process among people with presumed tuberculosis in Central Uganda

Uganda has improved its tuberculosis (TB) diagnostic processes over the years since the scale up of the Xpert MTB/RIF testing in 2012. However, there are continued delays in diagnosis and missing people with TB who are either not diagnosed or notified. We explored facilitators and barriers for completion of the TB diagnostic process among people with presumed TB in selected health facilities in Central Uganda. This was a qualitative exploration involving 25 in-depth interviews with people with presumed TB and six sex stratified focus group discussions with people with TB who had recently initiated treatment. We also conducted 20 key informant interviews with health workers providing TB services. All interviews and discussions were audio recorded and transcribed verbatim. Thematic analysis was carried out using Atlas.ti software version 6.0 guided by the constructs of the socio-ecological model. Key facilitators for completion of the TB diagnostic process included; individual factors (persistent symptoms and the desire to get better, obtaining same day results and prior TB knowledge); community (social support); and health system factors (caring health workers and calling of patients to collect results). Barriers were; individual factors (TB and HIV stigma, inability to produce sputum, lack of transport to return to the health facility); and health system factors (long turnaround time of results, stock out of supplies, unclear appointment for collection of results, inadequate patient contact details and negative health worker attitude). Completion of the TB diagnostic process is influenced by individual, health system and community related factors. To enhance completion, there is need for availing same day results, making clear appointments for collection of results and improving health worker attitudes at the health facility level. At the individual and community level, TB/HIV stigma reduction interventions, community health education on TB and provision of social support to patients with presumed TB should be emphasized.

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Publication Details

Journal
PLOS Global Public Health
Published
2025-09-19
DOI
https://doi.org/10.1371/journal.pgph.0004808
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
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article

Facilitators and barriers for completion of the diagnostic process among people with presumed tuberculosis in Central Uganda

Esther Buregyeya, Vicent Kasiita, Rebecca Nuwematsiko, Elizeus Rutebemberwa et al.
PLOS Global Public Health
Tuberculosis Research and Epidemiology
article

Facilitators and barriers for completion of the diagnostic process among people with presumed tuberculosis in Central Uganda

Esther Buregyeya, Vicent Kasiita, Rebecca Nuwematsiko, Elizeus Rutebemberwa, Angella Musiimenta, Lynn Atuyambe, Noah Kiwanuka
article en

Abstract

Uganda has improved its tuberculosis (TB) diagnostic processes over the years since the scale up of the Xpert MTB/RIF testing in 2012. However, there are continued delays in diagnosis and missing people with TB who are either not diagnosed or notified. We explored facilitators and barriers for completion of the TB diagnostic process among people with presumed TB in selected health facilities in Central Uganda. This was a qualitative exploration involving 25 in-depth interviews with people with presumed TB and six sex stratified focus group discussions with people with TB who had recently initiated treatment. We also conducted 20 key informant interviews with health workers providing TB services. All interviews and discussions were audio recorded and transcribed verbatim. Thematic analysis was carried out using Atlas.ti software version 6.0 guided by the constructs of the socio-ecological model. Key facilitators for completion of the TB diagnostic process included; individual factors (persistent symptoms and the desire to get better, obtaining same day results and prior TB knowledge); community (social support); and health system factors (caring health workers and calling of patients to collect results). Barriers were; individual factors (TB and HIV stigma, inability to produce sputum, lack of transport to return to the health facility); and health system factors (long turnaround time of results, stock out of supplies, unclear appointment for collection of results, inadequate patient contact details and negative health worker attitude). Completion of the TB diagnostic process is influenced by individual, health system and community related factors. To enhance completion, there is need for availing same day results, making clear appointments for collection of results and improving health worker attitudes at the health facility level. At the individual and community level, TB/HIV stigma reduction interventions, community health education on TB and provision of social support to patients with presumed TB should be emphasized.

PLOS Global Public HealthVol. 5(9)
Mbarara University of Science and Technology (UG), Infectious Diseases Institute (UG), Makerere University (UG)
Openalex Percentile: Top 70%
Tuberculosis Research and Epidemiology
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