Molecular mechanisms of dragon’s blood in treating ulcerative colitis based on NF-κb/NLPR3/Caspase-1 pyroptosis signaling pathway
DB acts through a multi-component, multi-target, and multi-pathway strategy. Inhibiting the NF-κB/NLPR3/Caspase-1 pyroptosis pathway positions NLPR3 as a viable target for DB in UC intervention.
Authors
- Xiaogang Huang (ORCID: https://orcid.org/0000-0001-6544-1278)
- Xiao‐Hua Qin (ORCID: https://orcid.org/0000-0001-8355-3230)
- Yilei Wen (ORCID: https://orcid.org/0000-0002-4078-2460)
- Hua Zhong (ORCID: https://orcid.org/0000-0002-9120-2323)
- Yuan Yu (ORCID: https://orcid.org/0000-0001-5453-2377)
- X. T. He (ORCID: https://orcid.org/0000-0002-7033-7640)
- Jing Cui (ORCID: https://orcid.org/0000-0002-1496-1828)
- B Cai
Institutions
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
- Guangxi University of Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1371/journal.pone.0331570
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81