Colorectal cancer tumor phenotypes associated with <i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> hot-spot mutations
Our findings support the potential prognostic utility of specific <i>KRAS</i> (p.Gly12Val, p.Gly12Asp, and p.Gly13Asp) and <i>BRAF</i> p.Val600Glu mutations in CRC. These results are preliminary and require validation through larger, multi-center studies before they can be considered reliable in clinical practice.
Authors
- Anthony O. Okorodudu (ORCID: https://orcid.org/0009-0003-6918-1217)
- Jianli Dong (ORCID: https://orcid.org/0000-0001-8929-6132)
- Yu‐Wei Cheng (ORCID: https://orcid.org/0000-0002-0114-9822)
- Yong‐Fang Kuo (ORCID: https://orcid.org/0000-0003-1927-0927)
- Omer Abdelgadir (ORCID: https://orcid.org/0009-0002-6104-0156)
- M. Firoze Khan
Institutions
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- World Journal of Gastrointestinal Pathophysiology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.4291/wjgp.v16.i3.107954
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00