Single‐time‐point tumor dosimetry using population‐based model selection and nonlinear mixed‐effects modeling in [ <sup>177</sup> Lu]Lu‐PSMA‐617 therapy

Our findings demonstrate that a single SPECT/CT measurement at 3 days after injection may be used to estimate tumor TIAVs in [<sup>177</sup>Lu]Lu-PSMA-617 therapy using the NLME method and PBMS.

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Publication Details

Journal
Medical Physics
Published
2025-09-18
DOI
https://doi.org/10.1002/mp.70000
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Single‐time‐point tumor dosimetry using population‐based model selection and nonlinear mixed‐effects modeling in [ 177 Lu]Lu‐PSMA‐617 therapy

Michael Mix, Ade Riana, Philipp T. Meyer, Felix Kind et al.
Medical Physics
Radiopharmaceutical Chemistry and Applications
article

Single‐time‐point tumor dosimetry using population‐based model selection and nonlinear mixed‐effects modeling in [ 177 Lu]Lu‐PSMA‐617 therapy

Michael Mix, Ade Riana, Philipp T. Meyer, Felix Kind, U. Nemer, Elham Yousefzadeh‐Nowshahr, Indra Budiansah, Ambros J. Beer, Gerhard Glatting, Deni Hardiansyah
article en

Abstract

Our findings demonstrate that a single SPECT/CT measurement at 3 days after injection may be used to estimate tumor TIAVs in [<sup>177</sup>Lu]Lu-PSMA-617 therapy using the NLME method and PBMS.

Medical PhysicsVol. 52(10)
Universität Ulm (DE), Stellenbosch University (ZA), University Medical Center Freiburg (DE), University of Indonesia (ID), Advanced Materials and Devices (United States) (US), University Hospital Ulm (DE), Technische Hochschule Ulm (DE)
Openalex Percentile: Top 62%
Radiopharmaceutical Chemistry and Applications
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