Impact of euploid blastocyst developmental stage and morphological grading on pregnancy outcomes in young recurrent pregnancy loss patients: association with parental chromosomal status
These findings suggest that the developmental stage of the blastocyst is the primary determinant of successful outcomes in BCT-associated RPL, whereas embryo morphological grading predominantly influences pregnancy outcomes in RPL patients with normal karyotypes. These results highlight the importance of personalized embryo selection strategies based on parental chromosomal status and embryological characteristics to optimize reproductive outcomes in distinct RPL.
Authors
- Cuilian Zhang (ORCID: https://orcid.org/0000-0002-5210-5272)
- Rui-Xiao Zhang (ORCID: https://orcid.org/0000-0002-4251-825X)
- T. Luo (ORCID: https://orcid.org/0000-0001-5188-8407)
- Chenchen Cui (ORCID: https://orcid.org/0000-0003-1019-5211)
Institutions
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Zhengzhou People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.3389/fendo.2025.1644773
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China