Metabolome profiling by untargeted metabolomics and biomarker panel selection using machine-learning for patients in different stages of peripheral neuropathy induced by oxaliplatin
These findings suggest that the selected biomarkers could serve as a foundation for the prediction and management of OIPN in colorectal cancer patients.
Authors
- Ruirong Wu
- Yongjuan Ding (ORCID: https://orcid.org/0000-0002-4918-503X)
- Yujiao Hua (ORCID: https://orcid.org/0000-0002-4227-9295)
- Jinghua Chen (ORCID: https://orcid.org/0000-0001-8122-8450)
- Yanyan Chen (ORCID: https://orcid.org/0000-0003-0888-2186)
- Ying Zhang (ORCID: https://orcid.org/0000-0001-8665-2744)
- Juan Lv (ORCID: https://orcid.org/0009-0000-4186-9018)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-4443-6458)
Institutions
- Jiangnan University (CN)
- Wuxi Fourth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.3389/fonc.2025.1617207
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00