Clinical outcomes of different 17β-estradiol drug regimens and their impact on endometrial receptivity

In FET cycles, a HRT regimen combining oral and vaginal administration of Micronized 17-beta estradiol hemihydrate is more conducive to endometrial growth. Although vaginal administration results in higher estrogen levels, it does not appear to compromise endometrial receptivity.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-09-19
DOI
https://doi.org/10.3389/fendo.2025.1639481
Citations
1
Primary Topic
Reproductive Biology and Fertility
Type
article
Field-Weighted Citation Impact
1.88
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Clinical outcomes of different 17β-estradiol drug regimens and their impact on endometrial receptivity

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article

Clinical outcomes of different 17β-estradiol drug regimens and their impact on endometrial receptivity

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article en
1 citations

Abstract

In FET cycles, a HRT regimen combining oral and vaginal administration of Micronized 17-beta estradiol hemihydrate is more conducive to endometrial growth. Although vaginal administration results in higher estrogen levels, it does not appear to compromise endometrial receptivity.

Frontiers in EndocrinologyVol. 16
Fujian Medical University (CN), Guilin Medical University (CN), Liuzhou Maternal and Child Health Hospital (CN), The People's Hospital of Guangxi Zhuang Autonomous Region (CN), Affiliated Hospital of Youjiang Medical University for Nationalities (CN), Second Affiliated Hospital of Fujian Medical University (CN), Baise University (CN), Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
Openalex Percentile: Top 12%
Reproductive Biology and Fertility
1.88
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