Gorlin-Goltz Syndrome in a Healthy Elderly Patient: A Case Report

Gorlin-Goltz syndrome (GGS), a rare inherited autosomal dominant disorder is characterized by presence of multiple basal cell carcinomas, odontogenic keratocyst (OKCs), bifid ribs or numerous skeletal and dental anomalies. A high level of expressiveness and penetrance is shown by this entity. It is therefore, necessary to understand the major and minor diagnostic criteria for the prompt diagnosis of this condition. We hereby report a case of a 50-year-old male who presented with multiple OKCs. On carrying out further investigations, bifid ribs and calcification of falx cerebri were additional findings which lead us to the diagnosis of GGS. It is therefore necessary to consider GGS as a possible diagnosis while dealing with any case of multiple OKCs

Authors

Publication Details

Journal
Oral Sciences Reports
Published
2025-09-19
DOI
https://doi.org/10.12982/osr.2025.067
Primary Topic
Hedgehog Signaling Pathway Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Gorlin-Goltz Syndrome in a Healthy Elderly Patient: A Case Report

Tejaswini Gaikwad, Sonali Waghmode, Sukanya Das, Sunil Kumar Mishra
Oral Sciences Reports
Hedgehog Signaling Pathway Studies
article

Gorlin-Goltz Syndrome in a Healthy Elderly Patient: A Case Report

Tejaswini Gaikwad, Sonali Waghmode, Sukanya Das, Sunil Kumar Mishra
article en

Abstract

Gorlin-Goltz syndrome (GGS), a rare inherited autosomal dominant disorder is characterized by presence of multiple basal cell carcinomas, odontogenic keratocyst (OKCs), bifid ribs or numerous skeletal and dental anomalies. A high level of expressiveness and penetrance is shown by this entity. It is therefore, necessary to understand the major and minor diagnostic criteria for the prompt diagnosis of this condition. We hereby report a case of a 50-year-old male who presented with multiple OKCs. On carrying out further investigations, bifid ribs and calcification of falx cerebri were additional findings which lead us to the diagnosis of GGS. It is therefore necessary to consider GGS as a possible diagnosis while dealing with any case of multiple OKCs

Oral Sciences ReportsVol. 46(3)
Openalex Percentile: Top 77%
Hedgehog Signaling Pathway Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.